1¡Perfora los cielos con tu taladro!
Kamina y Simon viven en el pueblo subterráneo de Giha, donde un Gunman gigante irrumpe en su casa. ¿Podrán derrotar al gigantesco intruso?
2¡Dije que pilotearé esa cosa!
Kamina y Simon se defienden de una nueva amenaza de los Gunmen. Kamina logra controlar a su propio Gunman para combatir contra los Hombres Bestia que libraron el ataque.
3¿Quién crees que eres, con tus dos caras?
Para detener a Viral, un imponente Hombre Bestia, y a su poderoso Gunman, los Gurren y los Lagann se unen para formar un nuevo Gunman: el Gurren-Lagann.
4Having Lots of Faces Doesn't Make You Great!
Team Gurren must work together with the eccentric Black Syblings to take down a Beastman foe on empty stomachs.
5I Don't Get It, Not One Bit!
Team Gurren must find their way out of a strange underground village where Gunmen are worshipped as divine beings.
6Sit in the Hot Tub 'Til You're Sick!!
Continuing to the Gunmen rallying point, Team Gurren finds themselves on a strange hot springs getaway.
7You're Gonna Do It!!
Thymilph, one of the Four Divine Generals of the mysterious Spiral King, arrives to support Viral's Enki, with the massive mobile Gunmen fortress, the Dai-Ganzan. Kamina and Simon pilot the Gurren-Lagann against seemingly overwhelming odds.
8Later, Buddy
Having temporarily stalled Viral and Thymilph in the last skirmish, the Team Gurren and their newly arrived allies join forces as "Team Dai-Gurren" and launch a decisive strike against the regrouping Gunmen force.
9What, Exactly, Is a Human?
Team Dai-Gurren managed to take control of the enemy fortress, but is still mourning the death of one of their own, especially Simon. After falling off a cliff, he notices a Gunman throw a capsule into a deep valley. Simon inspects it and finds he is able to open it with the same drill key he uses to pilot Lagann, and inside is a young human girl named Nia, but their introduction is cut short when an enemy Gunman appears.
10Who Is This Bro?
Nia true identity is revealed, as she flaunts her authority to get rid of another one of the Four Divine Generals, Adiane. The members of the Great Gurren Brigade are now suspicious of Nia and her true intentions, but she is only concerned about the depressed Simon. Adiane later returns to finish them all off, with Lordgenome's blessing.
11Simon, Hands Off
Team Dai-Gurren falls into a trap set by the third member of the Four Divine Generals, Guame. The Team is taken captive and stored underground to await execution. While digging an escape path, Simon finally understands Kamina's last words to him and after having a discussion with Guame, Nia finds out the reason why she was thrown away.
12Yoko, Will You Do Me a Favor?
Team Dai-Gurren are now on their way to Beastmen's capital city, Teppelin but there's a vast ocean in their way. The only way for them to get across is for the Dai-Gurren to be modified, so while they wait everyone goes to chill out at the beach. Once preparations are complete, the Great Gurren Brigade begins their cruise, but there's an ambush waiting for them.
13Eat Up Everyone!
Trying to do her part in Team Dai-Gurren, Nia decides to become a cook, but just before the crew have a taste of her dishes, Cytomander, the fourth member of the Divine Generals, launches an aerial attack on the Dai-Gurren. Simon leads the counter-attack on the Gurren-Lagann, this time accompanied by Yoko, who replaces a sick Rossiu.
14Well Met, Everyone
At last, Team Dai-Gurren arrives at the outskirts of Teppelin, but before aiming to the city, they must face a combined full-scale attack of Cytomander and Guame's forces.
15I Will Head Towards Tomorrow
The last of the Divine Generals fall, and the city of Teppelin collapses, revealing a Gunman of gigantic proportions. Simon and Nia struggle to pass through it in order to confront her father, the Spiral King himself.
16Compilation Episode
A recap of the story's events from the previous episodes.
17You Don't Know Anything!
During the following seven years, a new civilization rises and prospers under Simon's leadership. However, these peaceful times come to end when the threat mentioned in Lordgenome's last words starts to reveal itself.
18Tell Me the Secrets of This World
After the Anti-Spirals' first attack and Nia's astonishing announcement, Simon looks desperately for her, while Rossiu finally completes his secret project.
19We Will Survive By Any Means Necessary
To soothe the public opinion, Rossiu overthrows Simon and puts him under arrest. But when the Anti-Spirals launch a large-scale attack on Kamina City, he is left with no option but to let Simon engage the enemy using the Gurren-Lagann, not before resorting to extremes to put him under his control.
20How Far Will God Test Us?
As Simon arrives in prison, he unexpectedly meets Viral, who comments on how far he has fallen. Meanwhile, the truth about Rossiu's emergency plan and the consequences for those left behind on Earth are revealed.
21You Are Someone Who Ought to Survive
One year earlier, Yoko starts working as a schoolteacher on an island until she learns of the situation at Teppelin and returns to break Simon free. Once again reunited, Simon and the members of Team Dai-Gurren launch themselves into space to protect the Arc-Gurren from the enemy forces, now accompanied by Viral as co-pilot of the Gurren-Lagann.
22This Is My Final Duty!
The Gurren-Lagann and the Arc-Gurren join together to form the massive Arc-Gurren-Lagann and stop the Human Annihilation System.
23Let's Go, This Is the Final Battle
The members of Team Dai-Gurren make their preparations for the imminent war against the Anti-Spirals, but Rossiu is missing. However, when Kinon tells Simon about what he really intends to do, both start to look desperately for him.
24I'll Never Forget This Minute, This Second
Guided by Simon and Nia's feelings for each other, Team Dai-Gurren break through dimensions in search for the Anti-Spirals' homeworld. But after falling into the enemy's trap, they end up losing some of their most precious members, due to its vicious offensive.
25I Accept Your Last Wish!
Team Dai-Gurren struggles to escape from the ocean of despair created by the Anti-Spirals without success, until history repeats itself, as another irreplaceable member of the Team sacrifices himself to save the others.
26Let's Go, Buddy
After finally transforming their flagship into the Super Galactic Gurren-Lagann, Simon and his friends successfully fight back against the enemy. When their enemy starts to use their own memories and desires against them, Kamina reappears to help.
27The Lights in the Sky Are Stars
At last, Simon and Nia are reunited, and by combining the power of its members, Team Dai-Gurren creates the galaxy-sized Tengen Toppa Gurren-Lagann, and engage the Anti-Spiral threat in a decisive battle to determine the fate of the universe.