1La fragilidad del reino
Columbus' voyage is a success but a storm forces him to land on Portugal. The royals travel to Barcelona to sign a treaty with France, who ambitions to conquer Naples. The queen meets her new confessor, and her daughter ponders her future.
2Gobernar con mano dura
Columbus hides his doubts as he is pressed to make a second voyage. Portugal disputes the new lands to Castile, and France invades Italy. In Rome, the Pope juggles the rival countries interests for his own benefit.
3Nacidos para gobernar
4Atracción fatal
5El drama llega a la corte
6Reina de toda la península
7Muere la Príncesa de Asturias
8A Isabel le supera la tragedia
9Felipe y Juana llegan a sus reinos
10Isabel y Fernando o Juana y Felipe
11La llamaban Juana 'La loca'
12¿Conservarán el legado de Isabel?
13La muerte de Isabel