- 1
Luke Wilson, Julie Chen, Lee Brice
- 2
Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers
- 3
Steve Buscemi, Indy Car Season Champ, Alt-J
- 4
Tina Fey, Moody McCarthy, Kevin Drew
- 5
Bill Maher, Henrik Lundqvist, Spoon
- 6
Michael Strahan, Richard Branson, Interpol
- 7
Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson
- 8
Jason Bateman, Billy Eichner, Ryan Adams
- 9
Mindy Kaling, Jake Johannsen, Maddie & Tae
- 10
Mark Harmon, "Jungle" Jack Hanna
- 11
Denzel Washington, Lenny Kravitz
- 12
Kelly Ripa, Jim Gaffigan, Paloma Faith
- 13
Jerry Seinfeld, Michael Jackson ONE
- 14
Ted Danson, Andrew Norelli
- 15
Neil Patrick Harris, Jamie Oliver, Aretha Franklin
- 16
John Oliver, Maggie Q, Bleachers
- 17
Bill O'Reilly, Cristin Milioti
- 18
Johnny Galecki, Andre Benjamin, Delta Spirit
- 19
Mariska Hargitay, Simon Amstell, Kandace Springs
- 20
Aziz Ansari, Tom Dreesen
- 21
Robert Downey Jr., Sarah Paulson, Lizzo
- 22
Anderson Cooper, Gina Rodriguez, Hatsune Miku
- 23
Robert Duvall, Elle Fanning, Rival Sons
- 24
Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley
TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs.
- 25
Russell Brand, Dave Grohl, Foo Fighters
- 26
Michael Keaton, Foo Fighters
- 27
Bill Murray, Foo Fighters
- 28
Tom Selleck, Jenny Slate, Foo Fighters
- 29
Jessica Chastain, Lenny Marcus, Foo Fighters
- 30
Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis
- 31
Taylor Swift, Tom Mison
- 32
Jim Carrey, David Tennant
- 33
Brian Williams, Perfume Genius
- 34
Keith Olbermann, Brian Regan, Run the Jewels
- 35
Martin Short, Father John Misty
- 36
Jennifer Lopez, Rob Riggle, Kimbra
- 37
Whoopi Goldberg, Jimmy Page, Mapei
- 38
Amy Schumer, Jeff Caldwell
- 39
Katie Holmes, Alex Zanardi
- 40
Steve Carell, Martha Stewart, OK Go
- 41
Jennifer Lawrence, Boris Johnson
- 42
Jon Stewart, Shawn Mendes
- 43
Kristin Chenoweth; Chris Young
Actress Kristin Chenoweth; Chris Young performs.
- 44
Jason Sudeikis, Allison Janney, Damien Rice
- 45
Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger
- 46
Regis Philbin, Hundred Waters
- 47
Edward Norton, Jessye Norman
- 48
Norman Lear, TV on the Radio
- 49
Seth Rogen, Amy Sedaris
- 50
Emily Blunt, Adam Resnick, Wu-Tang Clan
- 51
Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz
- 52
Joaquin Phoenix, Cristela Alonzo, Al Green
- 53
Ben Stiller, Olivia Munn, LaLa Brooks
- 54
Meryl Streep, Rebel Wilson, J. Cole
- 55
Chris Rock, Sting
- 56
Jamie Foxx, Robert Klein, Dan Penn
- 57
Emma Stone Top, Marcus Mariota, Bob Seger
- 58
New Holiday Toys, Anna Kendrick, Charli XCX
- 59
Tom Brokaw, Will Nelson & Billy Joe Shaver
- 60
Rosie O’Donnel,l Jeff Altman
- 61
Jay Thomas, Josh Brolin, Darlene Love
The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home).
- 62
Kathy Griffin, David Oyelowo, Lera Lynn
- 63
Ethan Hawke, Allison Williams, Parquet Courts
- 64
Julianne Moore, Catfish & the Bottlemen
- 65
Donald Trump, Chelsea Peretti, Foxygen
- 66
Michael Somerville, Nicole Atkins
- 67
Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones
- 68
Anderson Cooper, Shovels & Rope
- 69
Amanda Peet, Ryn Weaver
- 70
Larry David, Dan Patrick, Sleater-Kinney
- 71
Urban Meyer, Johnny Beehner, Ella Henderson
- 72
Louis CK, Nicolle Wallace, the Lone Bellow
- 73
Andrew Luck, Oscar Isaac, Drenge
- 74
Viola Davis, Ben Schwartz, Marty Stuart
- 75
John Oliver, Mayim Bialik, Death Cab for Cutie
- 76
Aziz Ansari, Brian Kiley, Ben Howard
- 77
Jack Hanna, Sharon Jones and the Dap-Kings
- 78
Dr. Phil McGraw, Robin Tunney, Diana Krall
- 79
Ryan Reynolds, Dierks Bentley
- 80
Martin Short, Bettye Lavette
- 81
Sienna Miller, Andy Kindler, Bob Mould
- 82
Steve Carell, Dr. Cornel West
- 83
Courtney Love, Chris Elliott, Rhiannon Giddens
- 84
Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear
- 85
Tom Hanks, Sturgill Simpson
- 86
Bill Hader, Pat McGann, Shakey Graves
- 87
Matthew Perry, Adam Scott, Kishi Bashi
- 88
Dakota Johnson, David Tochinskiy, Twin Shadow
- 89
Will Smith, Grizfolk
- 90
Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko
- 91
Kid Scientists, Sean Hayes, Judah & the Lion
- 92
Helen Mirren, the 2015 Daytona 500 winner, Steve Earle
- 93
Matthew Broderick, Ellie Kemper, JD McPherson
- 94
Julianna Margulies, Eric Ripert, Glass Animals
- 95
Kevin Spacey, Lily James, Alabama Shakes
- 96
Patricia Arquette, Will Butler
- 97
Kelsey Grammer, Stevie Wonder
- 98
Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew
- 99
Kevin Bacon, Jimmie Walker, Airborne Toxic Event
- 100
Shailene Woodley, Dr. Cornel West, Matthew E. White
- 101
Will Ferrell, Glen Hansard
- 102
Norm MacDonald, Theo James
- 103
Ben Stiller, Tove Lo
- 104
Bill O'Reilly, Aubrey Plaza
- 105
James Franco, Jake Johannsen, Action Bronson
- 106
Neil Patrick Harris, Charlie Cox, the Suffers
- 107
David Duchovny, Josh Gad, Houndmouth
- 108
Sen. Al Franken, Billy Eichner, David Sanborn
- 109
Kelly Ripa, Aasif Mandvi, Fat White Family
- 110
Mike Myers, Nick Griffin, Banks
- 111
Sarah Jessica Parker, Julie Chen, Asleep at the Wheel
- 112
Billy Crystal, Chris Russo, Chris Stapleton
- 113
Michael J. Fox, Iron & Wine, Ben Bridwell
- 114
Kevin James, Tom Dreesen, Tracy Chapman
115Alec Baldwin, John Mayer
- 116
John Travolta, Amy Schumer, the Waterboys
- 117
Piedmont Bird Callers, Paul Rudd
- 118
Bruce Willis, Dawes
- 119
Robert Downey Jr., Chris Russo, Elvis Costello
- 120
Jerry Seinfeld, Jason Isbell & Amanda Shires
- 121
Scarlett Johansson, John Mellencamp, Todd Rundgren
- 122
Michael Keaton, Future Islands
- 123
Jack Hanna, John Popper
- 124
First Lady Michelle Obama Hootie and the Blowfish
- 125
Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor
- 126
President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile
- 127
Reese Witherspoon, Nathan Lane, Mumford & Sons
- 128
Martin Short, Norah Jones
- 129
Tina Fey, First Aid Kit
- 130
Ray Romano, Brian Regan, Dave Matthews Band
- 131
Howard Stern, Don Rickles
- 132
Bill Clinton, Adam Sandler
- 133
Julia Roberts, Paul Shaffer, Ryan Adams
- 134
Al Pacino, George Clooney, Tom Waits
- 135
Oprah Winfrey, Norm Macdonald
- 136
Tom Hanks, Eddie Vedder
- 137
Bill Murray, Bob Dylan
- 138
The Final Late Show with David Letterman
6,028th broadcast
- 139
President Barack Obama/Will Ferrell/Brandi Carlile & the Avett Brothers
- 140
Reese Witherspoon/Nathan Lane/Mumford & Sons
- 141
Martin Short/Norah Jones
- 142
Tina Fey/First Aid Kit
- 143
Ray Romano/Brian Regan/Dave Matthews Band
- 144
Howard Stern/Don Rickles
- 145
Bill Clinton/Adam Sandler
- 146
Julia Roberts/Paul Shaffer/Ryan Adams
- 147
George Clooney/Tom Waits
- 148
Oprah Winfrey/Norm McDonald
- 149
Tom Hanks/Eddie Vedder
The final episode includes surprises, memorable highlights and the last Top Ten List.
- 150
Bill Murray/Bob Dylan
- 151
The Final Late Show with David Letterman